Focused protein degradation is being explored instead technique in cancer, whereby the natural protein degradation procedure is co-opted for therapeutic needs. Lately produced novel molecules called proteolysis-concentrating on chimeras (PROTACs) are heterobifunctional molecules with two ligands joined by a linker. 1 ligand binds on the ‘protein of interest’ (POI) and https://www.directivepublications.org/journal-of-clinical-breast-cancer/