Have a digenetic existence cycle, involving a motile, extracellular promastigote stage that parasitizes the alimentary tract of a sandfly vector and an immotile amastigote phase that survives and replicates within the phagolysosomes of mononuclear phagocytes [two,3]. Besides human beings, Most important hosts of Leishmania . Gene expression regulation by CDK12: https://aldousi554tep7.activosblog.com/profile