Sulfates are the key circulating conjugates of ethinyl estradiol and glucuronides predominate in urine. The first oxidative metabolite is 2-hydroxy ethinyl estradiol, fashioned from the CYP3A4 isoform of cytochrome P450. Part of the first-pass metabolism of ethinyl estradiol is thought to happen in gastrointestinal mucosa. Ethinyl estradiol could undergo enterohepatic https://whatisblisovife35578.blogs-service.com/61224696/what-is-blisovi-fe-for-dummies