Lumefantrine will lessen the level or influence of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Cigarette smoking enormously will increase the potential of suffering coronary heart attacks and strokes. Furthermore, smoking and using oral contraceptives greatly improve the likelihood of establishing and dying of heart problems. Some st... https://ralstone210lzl4.fliplife-wiki.com/user