Here, we display that conolidine, a all-natural analgesic alkaloid Employed in conventional Chinese medicine, targets ACKR3, thus giving extra evidence of a correlation involving ACKR3 and pain modulation and opening different therapeutic avenues to the remedy of Long-term pain. We are independently owned along with the thoughts expressed here https://conolidineahistoryofnatur22109.timeblog.net/68219963/facts-about-conolidine-revealed